

| 货号 | VK039033 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Venezuelan equine encephalitis virus (VEEV) | ||||
| 应用 | ELISA, Neutralization | ||||
| 同种型 | IgG | ||||
| 克隆号 | SKV16 | ||||
| 靶标 | E1 envelope glycoprotein, E2 envelope glycoprotein, EC:3.4.21.90, Precursor of protein E3/E2, Spike glycoprotein E1, Spike glycoprotein E2, Structural polyprotein, p130, p62, pE2 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P09592 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Structural polyprotein (Spike glycoprotein) is a ~138 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions. 1. Garmashova, N. et al. (2007) Journal of virology 81, 2472-84. PMID: 17108023 2. Garmashova, N. et al. (2007) Journal of virology 81, 13552-65. PMID: 17913819 3. Atasheva, S. et al. (2010) Journal of virology 84, 4158-71. PMID: 20147401 4. Carey, BD. et al. (2018) Journal of virology 92. PMID: 29769351 | ||||
| Note | For research use only |

SDS-PAGE for Anti-VEEV Spike glycoprotein Antibody (SKV16)



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