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Anti-Human CTLA-4 Recombinant Antibody (SAA2550) (HB651043)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HB651043
品牌abinScience
种属反应性Human
应用ELISA, WB
克隆类型Monoclonal
同种型scFv-His
克隆号SAA2550
经测试应用WB
靶标HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
纯化方式Purified by Nickel column.
Accession号P16410
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).

1. Schwartz, JC. et al. (2001) Nature 410, 604-8. PMID: 11279501
2. Stamper, CC. et al. (2001) Nature 410, 608-11. PMID: 11279502
3. Teft, WA. et al. (2006) Annual review of immunology 24, 65-97. PMID: 16551244
4. Linsley, PS. et al. (1991) The Journal of experimental medicine 174, 561-9. PMID: 1714933
5. Zheng, Y. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 1683-91. PMID: 18641304
6. Ramagopal, UA. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E4223-E4232. PMID: 28484017
NoteFor research use only
Isotype ControlAnti-Flag Tag (DYKDDDDK) Recombinant Antibody (M2) (YP666033)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD152/CTLA4 Antibody (SAA2550)

  • Western blot

    Western blot analysis was performed using anti-SCFV-His polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Recombinant protein 100ng

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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