



| 货号 | HB651043 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, WB | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | scFv-His | ||||
| 克隆号 | SAA2550 | ||||
| 经测试应用 | WB | ||||
| 靶标 | HA, Hemagglutinin, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | ||||
| 内毒素水平 | < 10 EU/mg | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Purified by Nickel column. | ||||
| Accession号 | P16410 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy). 1. Schwartz, JC. et al. (2001) Nature 410, 604-8. PMID: 11279501 2. Stamper, CC. et al. (2001) Nature 410, 608-11. PMID: 11279502 3. Teft, WA. et al. (2006) Annual review of immunology 24, 65-97. PMID: 16551244 4. Linsley, PS. et al. (1991) The Journal of experimental medicine 174, 561-9. PMID: 1714933 5. Zheng, Y. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 1683-91. PMID: 18641304 6. Ramagopal, UA. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E4223-E4232. PMID: 28484017 | ||||
| Note | For research use only | ||||
| Isotype Control | Anti-Flag Tag (DYKDDDDK) Recombinant Antibody (M2) (YP666033) |

SDS-PAGE for Anti-Human CD152/CTLA4 Antibody (SAA2550)

Western blot analysis was performed using anti-SCFV-His polyclonal antibody at 1ug/mL on various samples.
Lane 1: Recombinant protein 100ng





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