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Anti-Human IRF4 Monoclonal Antibody (1A518) (HS848035)

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概述
货号HS848035
品牌abinScience
描述
Anti-Human IRF4 Monoclonal Antibody (1A518) [1A518] (HS848035) is a mouse monoclonal antibody detecting IRF4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
同种型IgG
克隆号1A518
克隆类型Monoclonal
免疫原E. coli - derived recombinant human IRF4 (Glu130-Glu451).
靶标Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q15306
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interferon regulatory factor 4 (IRF4) is a ~51 kDa protein. Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human IRF4 Monoclonal Antibody (1A518)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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