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Anti-Human Endoglin/CD105 Monoclonal Antibody (1A610) (HB604025)

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概述
货号HB604025
品牌abinScience
描述
Anti-Human CD105/ENG Monoclonal Antibody (1A610) [1A610] (HB604025) is a mouse monoclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG
克隆号1A610
免疫原E. coli - derived recombinant human CD105/ENG (Thr27-Gly581).
靶标Endoglin, CD105, ENG
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P17813
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454
2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529
3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484
4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773
5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830
6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366
7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human CD105/ENG Monoclonal Antibody (1A610)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human Endoglin/CD105 Monoclonal Antibody (1A610)

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