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Anti-Human CD2AP Monoclonal Antibody (1A674) (HV416015)

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概述
货号HV416015
品牌abinScience
描述
Anti-Human CD2AP Monoclonal Antibody (1A674) [1A674] (HV416015) is a mouse monoclonal antibody detecting CD2AP in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG
克隆号1A674
免疫原E. coli - derived recombinant human CD2AP (Val2-Lys58).
靶标CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9Y5K6
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

CD2-associated protein (CD2AP) is a ~71 kDa protein. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.

1. Kirsch, KH. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 6211-6. PMID: 10339567
2. Monzo, P. et al. (2005) Molecular biology of the cell 16, 2891-902. PMID: 15800069
3. Elbediwy, A. et al. (2012) The Journal of cell biology 198, 677-93. PMID: 22891260
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human CD2AP Monoclonal Antibody (1A674)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CD2AP Monoclonal Antibody (1A674)

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