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Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A711) (HC155035)

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概述
货号HC155035
品牌abinScience
描述
Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A711) [1A711] (HC155035) is a mouse monoclonal antibody detecting SLC22A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG
克隆号1A711
免疫原E. coli - derived recombinant human SLC22A2/OCT2 (Gly44-Asp150).
靶标Solute carrier family 22 member 2, Organic cation transporter 2, hOCT2, SLC22A2
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O15244
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Solute carrier family 22 member 2 (SLC22A2/OCT2) is a ~62 kDa protein. Electrogenic voltage-dependent transporter that mediates the transport of a variety of organic cations such as endogenous bioactive amines, cationic drugs and xenobiotics. Functions as a Na(+)-independent, bidirectional uniporter. Cation cellular uptake or release is driven by the electrochemical potential, i.e. membrane potential and concentration gradient. However, may also engage electroneutral cation exchange when saturating concentrations of cation substrates are reached.

1. Gorboulev, V. et al. (1997) DNA and cell biology 16, 871-81. PMID: 9260930
2. Busch, AE. et al. (1998) Molecular pharmacology 54, 342-52. PMID: 9687576
3. Winter, TN. et al. (2011) Molecular pharmaceutics 8, 133-42. PMID: 21128598
4. Urakami, Y. et al. (2004) Pharmaceutical research 21, 976-81. PMID: 15212162
5. Kimura, N. et al. (2005) Pharmaceutical research 22, 255-9. PMID: 15783073
6. Amphoux, A. et al. (2006) Neuropharmacology 50, 941-52. PMID: 16581093
7. Taubert, D. et al. (2007) PloS one 2, e385. PMID: 17460754
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Anti-Human SLC22A2/OCT2 Monoclonal Antibody (1A711)

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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