Anti-CHD4 Polyclonal Antibody (HC562014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HC562014

品牌

abinScience

描述

Anti-CHD4 Polyclonal Antibody (HC562014) is a rabbit polyclonal antibody detecting CHD4 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human CHD4 (Thr1706-Gln1912).

靶标

ATP-dependent helicase CHD4, CHD-4, CHD4, Chromodomain-helicase-DNA-binding protein 4, EC:3.6.4.-, Mi-2 autoantigen 218 kDa protein, Mi2-beta

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q14839

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Q14839

背景

ATP-dependent chromatin remodeler CHD4 is a ~218 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination. Involved in neurogenesis.

1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666

2. Farnung, L. et al. (2020) eLife 9. PMID: 32543371

3. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440

4. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165

5. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427

6. Gong, F. et al. (2015) Genes & development 29, 197-211. PMID: 25593309

Note

For research use only

图片

Western blot

Western blot analysis was performed using anti-CHD4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate

参考文献

产品说明书

Anti-CHD4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CHD4 Polyclonal Antibody (HC562014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CHD4 Polyclonal Antibody (HC562014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价