

| 货号 | HD433014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-GNL2 Polyclonal Antibody (HD433014) is a rabbit polyclonal antibody detecting GNL2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
| ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GNL2 (Glu195-Arg455). | ||||||||
| 靶标 | Autoantigen NGP-1, GNL2, NGP1, Nucleolar GTP-binding protein 2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q13823 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 别名 | Q13823 | ||||||||
| 背景 | Nucleolar GTP-binding protein 2 (GNL2) is a ~83 kDa protein. GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels. 1. Liang, X. et al. (2020) Nature communications 11, 3542. PMID: 32669547 2. Datta, D. et al. (2015) The Journal of biological chemistry 290, 21536-52. PMID: 26203195 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-GNL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate



24小时产品查询

扫一扫关注我们

专属渠道经理