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Anti-Human NLRP2 Polyclonal Antibody (HD439014)

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规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HD439014
品牌abinScience
描述
Anti-Human NLRP2 Polyclonal Antibody (HD439014) is a rabbit polyclonal antibody detecting NLRP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NLRP2 (Glu614-Glu1046).
靶标NACHT, LRR and PYD domains-containing protein 2, NALP2, NBS1, NLRP2, Nucleotide-binding site protein 1, PAN1, PYPAF2, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q9NX02
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Q9NX02
背景

NACHT, LRR and PYD domains-containing protein 2 (NLRP2) is a ~120 kDa protein. Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases.

NoteFor research use only
图片
  • Western blot

    Western blot analysis was performed using anti-NLRP2 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: A549 cell lysate
    Lane 2: K562 cell lysate

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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