

| 货号 | HD439014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human NLRP2 Polyclonal Antibody (HD439014) is a rabbit polyclonal antibody detecting NLRP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NLRP2 (Glu614-Glu1046). | ||||||||
| 靶标 | NACHT, LRR and PYD domains-containing protein 2, NALP2, NBS1, NLRP2, Nucleotide-binding site protein 1, PAN1, PYPAF2, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9NX02 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 别名 | Q9NX02 | ||||||||
| 背景 | NACHT, LRR and PYD domains-containing protein 2 (NLRP2) is a ~120 kDa protein. Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-NLRP2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: A549 cell lysate
Lane 2: K562 cell lysate



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