

| 货号 | HD441014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PEPD Polyclonal Antibody (HD441014) is a rabbit polyclonal antibody detecting PEPD in ELISA, IHC, WB. Suitable for Mouse, Rat, and Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PEPD (Thr188-Lys493). | ||||||||
| 靶标 | EC:3.4.13.9, Imidodipeptidase, PEPD, PRD, Peptidase D, Prolidase, Proline dipeptidase, X-Pro dipeptidase, Xaa-Pro dipeptidase | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P12955 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 别名 | P12955 | ||||||||
| 背景 | Xaa-Pro dipeptidase (PEPD) is a ~54 kDa protein. Dipeptidase that catalyzes the hydrolysis of dipeptides with a prolyl (Xaa-Pro) or hydroxyprolyl residue in the C-terminal position. The preferred dipeptide substrate is Gly-Pro, but other Xaa-Pro dipeptides, such as Ala-Pro, Met-Pro, Phe-Pro, Val-Pro and Leu-Pro, can be cleaved. Plays an important role in collagen metabolism because the high level of iminoacids in collagen. 1. Lupi, A. et al. (2006) The FEBS journal 273, 5466-78. PMID: 17081196 2. Rao, SD. et al. (2022) Nature chemical biology 18, 565-574. PMID: 35165443 3. Endo, F. et al. (1989) The Journal of biological chemistry 264, 4476-81. PMID: 2925654 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-PEPD polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: SH-SY5Y cell lysate



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