

| 货号 | HB941246 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Aflibercept (HB941246) is a research-grade recombinant antibody targeting L-VEGF.
Highlights
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| 种属反应性 | Human | ||||
| 应用 | ELISA, Functional assay, Research in vivo | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG1 Fc | ||||
| 靶标 | L-VEGF, N-VEGF, VEGF, VEGFA, VPF, Vascular endothelial growth factor A, long form, Vascular permeability factor | ||||
| 内毒素水平 | < 10 EU/mg | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P15692 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Vascular endothelial growth factor A, long form (VEGFA) is a ~43 kDa protein. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A. Involved in protecting cells from hypoxia-mediated cell death. VEGFA is the therapeutic target of bevacizumab (Avastin). 1. Katsman, M. et al. (2022) Cells 11. PMID: 35455969 | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SDS-PAGE for Research Grade Aflibercept



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