Anti-Monkey CD3 epsilon Recombinant Antibody (SAA2708) (HD679207)

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货号	HD679207
品牌	abinScience
种属反应性	Monkey
应用	ELISA, FCM
宿主	Mouse
克隆类型	Monoclonal
同种型	IgG2a
克隆号	SAA2708
靶标	CD3E, CD3e, T-cell surface glycoprotein CD3 epsilon chain
内毒素水平	<10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q95LI5
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	T-cell surface glycoprotein CD3 epsilon chain (CD3E) is a ~22 kDa protein. Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD3E ITAM phosphorylation creates docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. CD3E is the therapeutic target of blinatumomab (Blincyto).
Note	For research use only

产品说明书

Anti-Monkey CD3 epsilon Recombinant Antibody (SAA2708).pdf

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Anti-Monkey CD3 epsilon Recombinant Antibody (SAA2708) (HD679207)

概述

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参考文献

产品说明书

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重组蛋白

抗体

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实验相关试剂

Anti-Monkey CD3 epsilon Recombinant Antibody (SAA2708) (HD679207)

概述

图片

参考文献

产品说明书

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