Anti-Mouse/Rat/Human CD47 Recombinant Antibody (MIAP410) (HC359033)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC359033

abinScience

种属反应性

Human, Mouse, Rat

ELISA, FACS, Functional assay, Research in vivo

IgG1, kappa

MIAP410

Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6

内毒素水平

<1 EU/mg

>95% as determined by SDS-PAGE.

pH 7.4 Dilution Buffer

Protein A/G purified from cell culture supernatant.

Accession号

Q08722, Q61735, P97829

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Leukocyte surface antigen CD47 is a ~35 kDa protein. Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure.

1. Latour, S. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 2547-54. PMID: 11509594

2. Piccio, L. et al. (2005) Blood 105, 2421-7. PMID: 15383453

3. Isenberg, JS. et al. (2009) The Journal of biological chemistry 284, 1116-25. PMID: 19004835

4. Lindberg, FP. et al. (1993) The Journal of cell biology 123, 485-96. PMID: 7691831

5. Gao, AG. et al. (1996) The Journal of biological chemistry 271, 21-4. PMID: 8550562

6. Rogers, NM. et al. (2017) Cardiovascular research 113, 15-29. PMID: 27742621

7. Ghimire, K. et al. (2020) Cells 9. PMID: 32679764

For research use only

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

产品说明书

Anti-Mouse/Rat/Human CD47 Recombinant Antibody (MIAP410).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse/Rat/Human CD47 Recombinant Antibody (MIAP410) (HC359033)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse/Rat/Human CD47 Recombinant Antibody (MIAP410) (HC359033)

概述

图片

参考文献

产品说明书

相关产品推荐

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