

| 货号 | ARO-A12957 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) [1G2] (ARO-A12957) is a human monoclonal antibody detecting Envelope glycoprotein B, gB, gB, UL55 in ELISA, Neutralization. Suitable for Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5).
Highlights
|
| 种属反应性 | Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5) |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | 1G2 |
| 克隆类型 | Monoclonal |
| 靶标 | Envelope glycoprotein B, gB, gB, UL55 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P13201 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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