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InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (ARO-A13038)

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概述
货号ARO-A13038
品牌ProteoGenix
描述
InVivoMAb Anti-DENV-1/2/3/4 Envelope protein E/DII-FL region Antibody (1C19) (ARO-A13038) Purity: >95% as determined by SDS-PAGE..
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1), Dengue virus type 2 (strain Jamaica/1409/1983) (DENV-2), Dengue virus type 3 (strain Philippines/H87/1956) (DENV-3), Dengue virus type 4 (strain Dominica/814669/1981) (DENV-4)
应用ELISA, Neutralization
宿主Human
同种型IgG1, kappa
克隆号1C19
克隆类型Monoclonal
靶标Genome polyprotein, Envelope protein E, DII-FL region
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P17763, P07564, P27915, P09866
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.

1. Kuhn, RJ. et al. (2002) Cell 108, 717-25. PMID: 11893341
2. Sangiambut, S. et al. (2008) The Journal of general virology 89, 1254-1264. PMID: 18420804
3. Colpitts, TM. et al. (2011) PloS one 6, e24365. PMID: 21909430
4. Bhuvanakantham, R. et al. (2013) Cellular microbiology 15, 1688-706. PMID: 23522008
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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