

| 货号 | ARO-A13129 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-Nipah virus/NiV Prefusion Antibody (1H8) [1H8] (ARO-A13129) is a human monoclonal antibody detecting Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F in ELISA, Neutralization. Suitable for Nipah virus.
Highlights
|
| 种属反应性 | Nipah virus |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1 |
| 克隆号 | 1H8 |
| 克隆类型 | Monoclonal |
| 靶标 | Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q9IH63 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Fusion glycoprotein F0 is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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