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InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144) (ARO-A13376)

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概述
货号ARO-A13376
品牌ProteoGenix
描述
InVivoMAb Anti-Bordetella pertussis cyaA/Cyclolysin Antibody (Iv0144) [Iv0144] (ARO-A13376) is a human monoclonal antibody detecting Bifunctional hemolysin/adenylate cyclase, AC-HLY, ACT, Cyclolysin, Calmodulin-sensitive adenylate cyclase, 4.6.1.1, ATP pyrophosphate-lyase, Adenylyl cyclase, Hemolysin, cya, cyaA, BP0760 in ELISA. Suitable for Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
Highlights
  • Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
  • Validated for ELISA — Optimized for consistent performance.
种属反应性Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
应用ELISA
宿主Human
同种型IgG1
克隆号Iv0144
克隆类型Monoclonal
靶标Bifunctional hemolysin/adenylate cyclase, AC-HLY, ACT, Cyclolysin, Calmodulin-sensitive adenylate cyclase, 4.6.1.1, ATP pyrophosphate-lyase, Adenylyl cyclase, Hemolysin, cya, cyaA, BP0760
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P0DKX7
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Bifunctional hemolysin/adenylate cyclase (cyaA/Cyclolysin) is a ~177 kDa protein. Bifunctional adenylate cyclase toxin-hemolysin that plays a crucial role in host colonization. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function.

1. Glaser, P. et al. (1991) The EMBO journal 10, 1683-8. PMID: 2050107
2. Glaser, P. et al. (1989) The EMBO journal 8, 967-72. PMID: 2542030
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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