

| 货号 | ARO-A13330 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-Rotavirus A/RV-A Intermediate capsid protein VP6 (Iv0012) (ARO-A13330) Purity: >95% as determined by SDS-PAGE..
Highlights
|
| 种属反应性 | Rotavirus A (strain RVA/Monkey/United States/RRV/1975/G3P5B[3]) (RV-A) |
| 应用 | ELISA, Neutralization |
| 宿主 | Mouse |
| 同种型 | IgG2a, kappa |
| 克隆号 | Iv0012 |
| 克隆类型 | Monoclonal |
| 靶标 | Intermediate capsid protein VP6 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | B2BN53 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Intermediate capsid protein VP6 is a ~44 kDa protein. Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP. 1. Settembre, EC. et al. (2011) The EMBO journal 30, 408-16. PMID: 21157433 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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