

| 货号 | ARO-A13339 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-HPV16 L2/Minor capsid protein L2 (Iv0015) (ARO-A13339) Purity: >95% as determined by SDS-PAGE..
Highlights
|
| 种属反应性 | Human papillomavirus type 16 |
| 应用 | ELISA, Neutralization, WB |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | Iv0015 |
| 克隆类型 | Monoclonal |
| 靶标 | Minor capsid protein L2, L2 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P03107 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Minor capsid protein L2 is a ~50 kDa protein. Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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