InVivoMAb Anti-HPV B19/B19V NS1/Non-structural protein 1 (Iv0007) (ARO-A13366)

概述
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参考文献

概述

货号	ARO-A13366
品牌	ProteoGenix
描述	InVivoMAb Anti-HPV B19/B19V NS1/Non-structural protein 1 (Iv0007) (ARO-A13366) Purity: >95% as determined by SDS-PAGE.. Highlights Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human parvovirus B19 (strain HV) (HPV B19), Human parvovirus B19 (isolate AU) (HPV B19)
应用	ELISA, Neutralization
宿主	Human
同种型	IgG1, kappa
克隆号	Iv0007
克隆类型	Monoclonal
靶标	Initiator protein NS1, NS1, 3.1.21.-, 3.6.4.12, NCVP1, Non-capsid protein NS-1, Non-structural protein 1, Non-structural protein NS1, NS1
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	pH 7.4 Dilution Buffer
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9PZT1, P07298
状态	Liquid
保存溶液	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Initiator protein NS1 (Non-structural protein 1) is a ~74 kDa protein. Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter. Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR). Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters. Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins. Up-regulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition. 1. Raab, U. et al. (2002) Virology 293, 86-93. PMID: 11853402 2. Tewary, SK. et al. (2014) Virology 449, 297-303. PMID: 24418564 3. Sanchez, JL. et al. (2016) Biochemistry 55, 6577-6593. PMID: 27809499 4. Moffatt, S. et al. (1996) Journal of virology 70, 8485-91. PMID: 8970971 5. Nakashima, A. et al. (2004) Virology 329, 493-504. PMID: 15518826 6. Wan, Z. et al. (2010) The Journal of clinical investigation 120, 3530-44. PMID: 20890043 7. Luo, Y. et al. (2013) Journal of virology 87, 12766-75. PMID: 24049177
Note	For research use only. Not suitable for clinical or therapeutic use.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-HPV B19/B19V NS1/Non-structural protein 1 (Iv0007) (ARO-A13366)

概述

图片

参考文献

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-HPV B19/B19V NS1/Non-structural protein 1 (Iv0007) (ARO-A13366)

概述

图片

参考文献

相关产品推荐

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