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Anti-Human SNX3 Polyclonal Antibody (ARO-A12752)

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概述
货号ARO-A12752
品牌ProteoGenix
描述
Anti-Human SNX3 Polyclonal Antibody (ARO-A12752) is a rabbit polyclonal antibody detecting SNX3, Protein SDP3, Sorting nexin-3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SNX3 (Met1-Ala162).
靶标SNX3, Protein SDP3, Sorting nexin-3
纯化方式Purified by antigen affinity column.
Accession号O60493
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sorting nexin-3 (SNX3) is a ~18 kDa protein. Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Can also bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC/VPS).

1. Harterink, M. et al. (2011) Nature cell biology 13, 914-923. PMID: 21725319
2. Harrison, MS. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 267-72. PMID: 24344282
3. McGough, IJ. et al. (2018) Nature communications 9, 3737. PMID: 30213940
4. Chua, RY. et al. (2013) Immunology 139, 30-47. PMID: 23237080
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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