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Anti-Human DCK Polyclonal Antibody (ARO-A12774)

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概述
货号ARO-A12774
品牌ProteoGenix
描述
Anti-Human DCK Polyclonal Antibody (ARO-A12774) is a rabbit polyclonal antibody detecting dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DCK (Met1-Leu260).
靶标dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK
纯化方式Purified by antigen affinity column.
Accession号P27707
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Deoxycytidine kinase (DCK) is a ~30 kDa protein. Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.

1. Sabini, E. et al. (2003) Nature structural biology 10, 513-9. PMID: 12808445
2. Sabini, E. et al. (2008) Journal of molecular biology 378, 607-21. PMID: 18377927
3. Hazra, S. et al. (2009) Biochemistry 48, 1256-63. PMID: 19159229
4. Chottiner, EG. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 1531-5. PMID: 1996353
5. Hazra, S. et al. (2010) Biochemistry 49, 6784-90. PMID: 20614893
6. Smal, C. et al. (2010) Archives of biochemistry and biophysics 502, 44-52. PMID: 20637175
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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