

| 货号 | ARO-A12774 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human DCK Polyclonal Antibody (ARO-A12774) is a rabbit polyclonal antibody detecting dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human DCK (Met1-Leu260). |
| 靶标 | dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P27707 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Deoxycytidine kinase (DCK) is a ~30 kDa protein. Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. 1. Sabini, E. et al. (2003) Nature structural biology 10, 513-9. PMID: 12808445 2. Sabini, E. et al. (2008) Journal of molecular biology 378, 607-21. PMID: 18377927 3. Hazra, S. et al. (2009) Biochemistry 48, 1256-63. PMID: 19159229 4. Chottiner, EG. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 1531-5. PMID: 1996353 5. Hazra, S. et al. (2010) Biochemistry 49, 6784-90. PMID: 20614893 6. Smal, C. et al. (2010) Archives of biochemistry and biophysics 502, 44-52. PMID: 20637175 |
| Note | For research use only. |

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