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Anti-Human MCRS1 Polyclonal Antibody (ARO-A12947)

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概述
货号ARO-A12947
品牌ProteoGenix
描述
Anti-Human MCRS1 Polyclonal Antibody (ARO-A12947) is a rabbit polyclonal antibody detecting MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human MCRS1 (Gln344-Gln462).
靶标MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein
纯化方式Purified by antigen affinity column.
Accession号Q96EZ8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

1. Lin, DY. et al. (2002) The Journal of biological chemistry 277, 25446-56. PMID: 11948183
2. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852
3. Song, H. et al. (2004) Biochemical and biophysical research communications 316, 1116-23. PMID: 15044100
4. Davidovic, L. et al. (2006) Human molecular genetics 15, 1525-38. PMID: 16571602
5. Fawal, MA. et al. (2015) Developmental cell 33, 67-81. PMID: 25816988
6. Meunier, S. et al. (2011) Nature cell biology 13, 1406-14. PMID: 22081094
7. Meunier, S. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 1779-86. PMID: 27192185
8. Yang, H. et al. (2019) Molecular biology of the cell 30, 1060-1068. PMID: 30785839
9. Laguillo-Diego, A. et al. (2023) Molecular biology of the cell 34, ar1. PMID: 36350698
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human MCRS1 Polyclonal Antibody

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