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Anti-Human RAB3A Polyclonal Antibody (ARO-A13420)

概述
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参考文献

概述

货号	ARO-A13420
品牌	ProteoGenix
描述	Anti-Human RAB3A Polyclonal Antibody (ARO-A13420) is a rabbit polyclonal antibody detecting Ras-related protein Rab-3A, RAB3A in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human RAB3A (Asp20-Thr193).
靶标	Ras-related protein Rab-3A, RAB3A
纯化方式	Purified by antigen affinity column.
Accession号	P20336
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Ras-related protein Rab-3A (RAB3A) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB3A plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane. Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane. 1. Zahraoui, A. et al. (1989) The Journal of biological chemistry 264, 12394-401. PMID: 2501306 2. Encarnação, M. et al. (2016) The Journal of cell biology 213, 631-40. PMID: 27325790 3. Bello, OD. et al. (2012) Experimental cell research 318, 478-88. PMID: 22248876 4. Quevedo, MF. et al. (2019) Biochimica et biophysica acta. Molecular cell research 1866, 612-622. PMID: 30599141
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human RAB3A Polyclonal Antibody

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