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Anti-Human YWHAG Polyclonal Antibody (ARO-A13410)

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概述
货号ARO-A13410
品牌ProteoGenix
描述
Anti-Human YWHAG Polyclonal Antibody (ARO-A13410) is a rabbit polyclonal antibody detecting Protein kinase C inhibitor protein 1, 14-3-3 protein gamma, YWHAG, KCIP-1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human YWHAG (Met1-Asn247).
靶标Protein kinase C inhibitor protein 1, 14-3-3 protein gamma, YWHAG, KCIP-1
纯化方式Purified by antigen affinity column.
Accession号P61981
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

14-3-3 protein gamma (YWHAG) is a ~28 kDa protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes inactivation of WDR24 component of the GATOR2 complex by binding to phosphorylated WDR24. Participates in the positive regulation of NMDA glutamate receptor activity by promoting the L-glutamate secretion through interaction with BEST1.

1. Yoshida, K. et al. (2005) Nature cell biology 7, 278-85. PMID: 15696159
2. Jin, Y. et al. (2006) The EMBO journal 25, 1207-18. PMID: 16511572
3. Dai, X. et al. (2023) Nature metabolism 5, 265-276. PMID: 36732624
4. Oh, SJ. et al. (2017) Molecular brain 10, 51. PMID: 29121962
5. Rietscher, K. et al. (2018) Journal of cell science 131. PMID: 29678907
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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