

| 货号 | ARO-A13392 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human JADE1 Polyclonal Antibody (ARO-A13392) is a rabbit polyclonal antibody detecting KIAA1807, Jade family PHD finger protein 1, JADE1, PHD finger protein 17, Protein Jade-1, PHF17 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human JADE1 (Gly217-Ser363). |
| 靶标 | KIAA1807, Jade family PHD finger protein 1, JADE1, PHD finger protein 17, Protein Jade-1, PHF17 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q6IE81 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Protein Jade-1 (JADE1) is a ~95 kDa protein. Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. 1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653 2. Saksouk, N. et al. (2009) Molecular cell 33, 257-65. PMID: 19187766 3. Miotto, B. et al. (2010) Molecular cell 37, 57-66. PMID: 20129055 4. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767 5. Panchenko, MV. et al. (2004) The Journal of biological chemistry 279, 56032-41. PMID: 15502158 6. Zhou, MI. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 11035-40. PMID: 16046545 7. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112 |
| Note | For research use only. |

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