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Anti-Human USP19 Polyclonal Antibody (ARO-A13430)

概述
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参考文献

概述

货号	ARO-A13430
品牌	ProteoGenix
描述	Anti-Human USP19 Polyclonal Antibody (ARO-A13430) is a rabbit polyclonal antibody detecting Deubiquitinating enzyme 19, Ubiquitin thioesterase 19, KIAA0891, ZMYND9, Ubiquitin carboxyl-terminal hydrolase 19, Ubiquitin-specific-processing protease 19, Zinc finger MYND domain-containing protein 9, USP19 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human USP19 (Lys286-Gln376).
靶标	Deubiquitinating enzyme 19, Ubiquitin thioesterase 19, KIAA0891, ZMYND9, Ubiquitin carboxyl-terminal hydrolase 19, Ubiquitin-specific-processing protease 19, Zinc finger MYND domain-containing protein 9, USP19
纯化方式	Purified by antigen affinity column.
Accession号	O94966
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Ubiquitin carboxyl-terminal hydrolase 19 (USP19) is a ~145 kDa protein. Deubiquitinating enzyme that regulates the degradation of various proteins by removing ubiquitin moieties, thereby preventing their proteasomal degradation. Stabilizes RNF123, which promotes CDKN1B degradation and contributes to cell proliferation. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. 1. Hassink, GC. et al. (2009) EMBO reports 10, 755-61. PMID: 19465887 2. Lee, JG. et al. (2014) The Journal of biological chemistry 289, 3510-7. PMID: 24356957 3. Mei, Y. et al. (2011) The Journal of biological chemistry 286, 35380-35387. PMID: 21849505 4. Altun, M. et al. (2012) The Journal of biological chemistry 287, 1962-9. PMID: 22128162 5. Chai, P. et al. (2021) The Journal of cell biology 220. PMID: 33978709 6. Yu, W. et al. (2024) Journal of Alzheimer's disease : JAD 100, 799-808. PMID: 38943386 7. Lei, CQ. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 259-268. PMID: 31127032 8. Xue, W. et al. (2020) The Biochemical journal 477, 4295-4312. PMID: 33094816
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human USP19 Polyclonal Antibody

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