

| 货号 | ARO-A11008 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-MARV GP1/Envelope glycoprotein 1 Polyclonal Antibody (ARO-A11008) for research applications.
Highlights
|
| 种属反应性 | Lake Victoria marburgvirus (strain Ravn-87) (MARV) (Marburg virus (strain Kenya/Ravn/1987)) |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant MARV GP1/Envelope glycoprotein 1 (Leu19-Gln205). |
| 靶标 | Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q1PDC7 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Envelope glycoprotein (GP1/Envelope glycoprotein 1) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection). |
| Note | For research use only. |

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