

| 货号 | ARO-A13493 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-HMPV SH/Small hydrophobic protein Polyclonal Antibody (ARO-A13493) for research applications.
Highlights
|
| 种属反应性 | Human metapneumovirus (strain CAN97-83) (HMPV) |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant HMPV SH/Small hydrophobic protein (Asn51-Asp179). |
| 靶标 | Small hydrophobic protein, SH |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q6WB95 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Small hydrophobic protein (SH) is a ~20 kDa protein. Viroporin that forms a ion channel probably displaying low ion selectivity. Plays a role in counteracting host innate immunity by inhibiting TLR7/MyD88/TRAF6 signaling and STAT1 phosphorylation, leading to down-regulation of type-I IFN. 1. Masante, C. et al. (2014) Journal of virology 88, 6423-33. PMID: 24672047 2. Hastings, AK. et al. (2016) Virology 494, 248-56. PMID: 27131212 3. Bao, X. et al. (2018) Viruses 10. PMID: 29789500 |
| Note | For research use only. |

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