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Anti-HMPV M2/Protein M2-2 Polyclonal Antibody (ARO-A13491)

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概述
货号ARO-A13491
品牌ProteoGenix
描述
Anti-HMPV M2/Protein M2-2 Polyclonal Antibody (ARO-A13491) for research applications.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human metapneumovirus (strain CAN97-83) (HMPV)
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant HMPV M2/Protein M2-2 (Thr2-Ser71).
靶标Protein M2-2, M2
纯化方式Purified by antigen affinity column.
Accession号Q6WB96
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein M2-2 is a ~8 kDa protein. Mediates the regulatory switch from transcription to RNA replication. Acts late in infection by inhibiting viral transcription and up-regulating RNA replication. Plays a major role in antagonizing the type I IFN-mediated antiviral response. Interacts with host MAVS and prevents the interaction with its upstream partner RIGI in the signaling pathway leading to interferon production. Inhibits host RIGI signaling by preventing TRIM25-mediated RIGI ubiquitination.

1. Ren, J. et al. (2012) Journal of virology 86, 13049-61. PMID: 23015697
2. Tanaka, Y. et al. (2022) Frontiers in immunology 13, 970750. PMID: 36045682
3. Ren, J. et al. (2014) PloS one 9, e91865. PMID: 24618691
4. Kitagawa, Y. et al. (2017) Journal of virology 91. PMID: 28768858
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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