

| 货号 | ARO-A11115 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Mouse CD275/ICOSLG Polyclonal Antibody (ARO-A11115) is a rabbit polyclonal antibody detecting ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
|
| 种属反应性 | Mouse |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Mouse CD275/ICOSLG (Glu47-Gln258). |
| 靶标 | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275) |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9JHJ8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | ICOS ligand (CD275/ICOSLG) is a ~35 kDa protein. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. 1. Swallow, MM. et al. (1999) Immunity 11, 423-32. PMID: 10549624 2. Yoshinaga, SK. et al. (1999) Nature 402, 827-32. PMID: 10617205 3. Ling, V. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 1653-7. PMID: 10657606 |
| Note | For research use only. |

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