

| 货号 | ARO-A11133 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human B4GALT6 Polyclonal Antibody (ARO-A11133) is a rabbit polyclonal antibody detecting b4Gal-T6, Beta4Gal-T6, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 6, Beta-1, 4-galactosyltransferase 6, Lactosylceramide synthase, UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase, Beta-1, 4-GalTase 6, Glucosylceramide beta-1, 4-galactosyltransferase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 6, B4GALT6 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human B4GALT6 (Glu125-Tyr382). |
| 靶标 | b4Gal-T6, Beta4Gal-T6, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 6, Beta-1, 4-galactosyltransferase 6, Lactosylceramide synthase, UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase, Beta-1, 4-GalTase 6, Glucosylceramide beta-1, 4-galactosyltransferase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 6, B4GALT6 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9UBX8 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Beta-1,4-galactosyltransferase 6 (B4GALT6) is a ~44 kDa protein. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. 1. Chatterjee, S. et al. (1992) The Journal of biological chemistry 267, 7148-53. PMID: 1551920 2. Yamaji, T. et al. (2014) PloS one 9, e88124. PMID: 24498430 3. Chatterjee, S. et al. (1987) Biochimica et biophysica acta 923, 136-42. PMID: 3099851 |
| Note | For research use only. |

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