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Anti-Human CEP19 Polyclonal Antibody (ARO-A11130)

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概述
货号ARO-A11130
品牌ProteoGenix
描述
Anti-Human CEP19 Polyclonal Antibody (ARO-A11130) is a rabbit polyclonal antibody detecting Centrosomal protein of 19 kDa, C3orf34, Cep19, CEP19 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CEP19 (Met1-Asp133).
靶标Centrosomal protein of 19 kDa, C3orf34, Cep19, CEP19
纯化方式Purified by antigen affinity column.
Accession号Q96LK0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Centrosomal protein of 19 kDa (CEP19) is a ~19 kDa protein. Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes.

1. Nishijima, Y. et al. (2017) Molecular biology of the cell 28, 1652-1666. PMID: 28428259
2. Kanie, T. et al. (2017) Developmental cell 42, 22-36.e12. PMID: 28625565
3. Mojarad, BA. et al. (2017) Open biology 7. PMID: 28659385
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CEP19 Polyclonal Antibody

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