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Anti-Human CTPS2 Polyclonal Antibody (ARO-A11195)

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概述
货号ARO-A11195
品牌ProteoGenix
描述
Anti-Human CTPS2 Polyclonal Antibody (ARO-A11195) is a rabbit polyclonal antibody detecting CTPS2, CTP synthetase 2, UTP--ammonia ligase 2, CTP synthase 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CTPS2 (Met1-Lys297).
靶标CTPS2, CTP synthetase 2, UTP--ammonia ligase 2, CTP synthase 2
纯化方式Purified by antigen affinity column.
Accession号Q9NRF8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

CTP synthase 2 (CTPS2) is a ~65 kDa protein. CTP synthase involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.

1. van Kuilenburg, AB. et al. (2000) Biochimica et biophysica acta 1492, 548-52. PMID: 10899599
2. Han, GS. et al. (2005) The Journal of biological chemistry 280, 38328-36. PMID: 16179339
3. Lynch, EM. et al. (2020) Nature structural & molecular biology 27, 42-48. PMID: 31873303
4. Lynch, EM. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34583994
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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