

| 货号 | ARO-A11185 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human CBLL1 Polyclonal Antibody (ARO-A11185) is a rabbit polyclonal antibody detecting CBLL1, RING-type E3 ubiquitin transferase Hakai, E3 ubiquitin-protein ligase Hakai, RING finger protein 188, c-Cbl-like protein 1, HAKAI, RNF188, Casitas B-lineage lymphoma-transforming sequence-like protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CBLL1 (Lys117-His190). |
| 靶标 | CBLL1, RING-type E3 ubiquitin transferase Hakai, E3 ubiquitin-protein ligase Hakai, RING finger protein 188, c-Cbl-like protein 1, HAKAI, RNF188, Casitas B-lineage lymphoma-transforming sequence-like protein 1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q75N03 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | E3 ubiquitin-protein ligase Hakai (CBLL1) is a ~54 kDa protein. E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown. 1. Yue, Y. et al. (2018) Cell discovery 4, 10. PMID: 29507755 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理