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Anti-Human HBS1L Polyclonal Antibody (ARO-A11199)

概述
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参考文献

概述

货号	ARO-A11199
品牌	ProteoGenix
描述	Anti-Human HBS1L Polyclonal Antibody (ARO-A11199) is a rabbit polyclonal antibody detecting HBS1L, KIAA1038, ERFS, HBS1, HBS1-like protein in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human HBS1L (Gly257-Lys478).
靶标	HBS1L, KIAA1038, ERFS, HBS1, HBS1-like protein
纯化方式	Purified by antigen affinity column.
Accession号	Q9Y450
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	HBS1-like protein (HBS1L) is a ~75 kDa protein. GTPase component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. The Pelota-HBS1L complex recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following mRNA extraction from stalled ribosomes by the SKI complex, the Pelota-HBS1L complex promotes recruitment of ABCE1, which drives the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway. 1. Pisareva, VP. et al. (2011) The EMBO journal 30, 1804-17. PMID: 21448132 2. Saito, S. et al. (2013) The Journal of biological chemistry 288, 17832-43. PMID: 23667253 3. Shao, S. et al. (2016) Cell 167, 1229-1240.e15. PMID: 27863242 4. Zinoviev, A. et al. (2020) Molecular cell 77, 1340-1349.e6. PMID: 32006463
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human HBS1L Polyclonal Antibody

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