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Anti-Mouse FLRT2 Polyclonal Antibody (ARO-A11116)

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概述
货号ARO-A11116
品牌ProteoGenix
描述
Anti-Mouse FLRT2 Polyclonal Antibody (ARO-A11116) is a rabbit polyclonal antibody detecting Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse FLRT2 (Cys36-Ser359).
靶标Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2)
纯化方式Purified by antigen affinity column.
Accession号Q8BLU0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Leucine-rich repeat transmembrane protein FLRT2 is a ~73 kDa protein. Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades.

1. Müller, PS. et al. (2011) Development (Cambridge, England) 138, 1297-308. PMID: 21350012
2. Seiradake, E. et al. (2014) Neuron 84, 370-85. PMID: 25374360
3. Jackson, VA. et al. (2015) Structure (London, England : 1993) 23, 774-81. PMID: 25728924
4. Yamagishi, S. et al. (2011) The EMBO journal 30, 2920-33. PMID: 21673655
5. Haines, BP. et al. (2006) Developmental biology 297, 14-25. PMID: 16872596
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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