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Anti-Human GPIHBP1 Polyclonal Antibody (ARO-A11214)

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概述
货号ARO-A11214
品牌ProteoGenix
描述
Anti-Human GPIHBP1 Polyclonal Antibody (ARO-A11214) is a rabbit polyclonal antibody detecting GPIHBP1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-anchored HDL-binding protein 1, HBP1, High density lipoprotein-binding protein 1, GPI-HBP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human GPIHBP1 (Ser59-Gln132).
靶标GPIHBP1, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-anchored HDL-binding protein 1, HBP1, High density lipoprotein-binding protein 1, GPI-HBP1
纯化方式Purified by antigen affinity column.
Accession号Q8IV16
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is a ~19 kDa protein. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5.

1. Mysling, S. et al. (2016) eLife 5. PMID: 27929370
2. Kristensen, KK. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E6020-E6029. PMID: 29899144
3. Beigneux, AP. et al. (2009) Arteriosclerosis, thrombosis, and vascular biology 29, 956-62. PMID: 19304573
4. Coca-Prieto, I. et al. (2011) Journal of internal medicine 270, 224-8. PMID: 21314738
5. Gin, P. et al. (2007) Biochimica et biophysica acta 1771, 1464-8. PMID: 17997385
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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