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Anti-HIF2A/EPAS1 Polyclonal Antibody (ARO-A11237)

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概述
货号ARO-A11237
品牌ProteoGenix
描述
Anti-HIF2A/EPAS1 Polyclonal Antibody (ARO-A11237) is a rabbit polyclonal antibody detecting Basic-helix-loop-helix-PAS protein MOP2, bHLHe73, HIF-2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, HIF2A, HLF, EPAS1, Endothelial PAS domain-containing protein 1, EPAS-1, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, MOP2, HIF2-alpha, BHLHE73, PASD2, Class E basic helix-loop-helix protein 73 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human HIF2A/EPAS1 (Leu239-Asn350).
靶标Basic-helix-loop-helix-PAS protein MOP2, bHLHe73, HIF-2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, HIF2A, HLF, EPAS1, Endothelial PAS domain-containing protein 1, EPAS-1, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, MOP2, HIF2-alpha, BHLHE73, PASD2, Class E basic helix-loop-helix protein 73
纯化方式Purified by antigen affinity column.
Accession号Q99814
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Endothelial PAS domain-containing protein 1 (HIF2A/EPAS1) is a ~96 kDa protein. Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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