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Anti-Human TERF1 Polyclonal Antibody (ARO-A11292)

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概述
货号ARO-A11292
品牌ProteoGenix
描述
Anti-Human TERF1 Polyclonal Antibody (ARO-A11292) is a rabbit polyclonal antibody detecting TRF1, PIN2, Telomeric protein Pin2/TRF1, TERF1, TTAGGG repeat-binding factor 1, TRF, Telomeric repeat-binding factor 1, NIMA-interacting protein 2, TRBF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TERF1 (Arg94-Ser253).
靶标TRF1, PIN2, Telomeric protein Pin2/TRF1, TERF1, TTAGGG repeat-binding factor 1, TRF, Telomeric repeat-binding factor 1, NIMA-interacting protein 2, TRBF1
纯化方式Purified by antigen affinity column.
Accession号P54274
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Telomeric repeat-binding factor 1 (TERF1) is a ~50 kDa protein. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.

1. Li, P. et al. (2019) International journal of biological sciences 15, 2350-2362. PMID: 31595153
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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