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Anti-Human POU4F2 Polyclonal Antibody (ARO-A11266)

概述
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参考文献

概述

货号	ARO-A11266
品牌	ProteoGenix
描述	Anti-Human POU4F2 Polyclonal Antibody (ARO-A11266) is a rabbit polyclonal antibody detecting POU domain, class 4, transcription factor 2, POU4F2, Brn-3B, BRN3B, Brain-3B, Brain-specific homeobox/POU domain protein 3B in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human POU4F2 (Gly246-Lys336).
靶标	POU domain, class 4, transcription factor 2, POU4F2, Brn-3B, BRN3B, Brain-3B, Brain-specific homeobox/POU domain protein 3B
纯化方式	Purified by antigen affinity column.
Accession号	Q12837
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	POU domain, class 4, transcription factor 2 (POU4F2) is a ~43 kDa protein. Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells. Functions either as activator or repressor modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner. Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding. 1. Salichs, E. et al. (2009) PLoS genetics 5, e1000397. PMID: 19266028 2. Zhang, L. et al. (2013) Molecular vision 19, 1371-86. PMID: 23805044
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

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浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human POU4F2 Polyclonal Antibody

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