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Anti-Human DNAJB6 Polyclonal Antibody (ARO-A11363)

概述
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参考文献

概述

货号	ARO-A11363
品牌	ProteoGenix
描述	Anti-Human DNAJB6 Polyclonal Antibody (ARO-A11363) is a rabbit polyclonal antibody detecting HHDJ1, Heat shock protein J2, MRJ, HSJ-2, HSJ2, MSJ-1, DnaJ homolog subfamily B member 6, DNAJB6, MSJ1 in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human DNAJB6 (Met1-Gly124).
靶标	HHDJ1, Heat shock protein J2, MRJ, HSJ-2, HSJ2, MSJ-1, DnaJ homolog subfamily B member 6, DNAJB6, MSJ1
纯化方式	Purified by antigen affinity column.
Accession号	O75190
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	DnaJ homolog subfamily B member 6 (DNAJB6) is a ~36 kDa protein. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Also reduces cellular toxicity and caspase-3 activity. 1. Izawa, I. et al. (2000) The Journal of biological chemistry 275, 34521-7. PMID: 10954706 2. Tsai, PC. et al. (2017) Clinical genetics 92, 150-157. PMID: 28233300 3. Chuang, JZ. et al. (2002) The Journal of biological chemistry 277, 19831-8. PMID: 11896048 4. Sarparanta, J. et al. (2012) Nature genetics 44, 450-5, S1-2. PMID: 22366786 5. Hageman, J. et al. (2010) Molecular cell 37, 355-69. PMID: 20159555
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human DNAJB6 Polyclonal Antibody

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