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Anti-DVL2 Polyclonal Antibody (ARO-A11377)

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概述
货号ARO-A11377
品牌ProteoGenix
描述
Anti-DVL2 Polyclonal Antibody (ARO-A11377) is a rabbit polyclonal antibody detecting Dishevelled-2, DVL2, DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DVL2 (Gly12-Ser92).
靶标Dishevelled-2, DVL2, DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2
纯化方式Purified by antigen affinity column.
Accession号O14641
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Segment polarity protein dishevelled homolog DVL-2 (DVL2) is a ~78 kDa protein. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

1. Geng, Y. et al. (2014) The Journal of biological chemistry 289, 11230-11241. PMID: 24616100
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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