

| 货号 | ARO-A11365 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human SS18L1 Polyclonal Antibody (ARO-A11365) is a rabbit polyclonal antibody detecting Calcium-responsive transactivator, CREST, SS18-like protein 1, KIAA0693, SS18L1, SYT homolog 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human SS18L1 (Thr17-Leu75). |
| 靶标 | Calcium-responsive transactivator, CREST, SS18-like protein 1, KIAA0693, SS18L1, SYT homolog 1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | O75177 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Calcium-responsive transactivator (SS18L1) is a ~42 kDa protein. Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. |
| Note | For research use only. |

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