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Anti-Human NPHP4 Polyclonal Antibody (ARO-A11364)

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概述
货号ARO-A11364
品牌ProteoGenix
描述
Anti-Human NPHP4 Polyclonal Antibody (ARO-A11364) is a rabbit polyclonal antibody detecting KIAA0673, Nephrocystin-4, NPHP4, Nephroretinin in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NPHP4 (His1171-Gln1426).
靶标KIAA0673, Nephrocystin-4, NPHP4, Nephroretinin
纯化方式Purified by antigen affinity column.
Accession号O75161
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Nephrocystin-4 (NPHP4) is a ~157 kDa protein. Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Required for building functional cilia. Involved in the organization of the subapical actin network in multiciliated epithelial cells. Seems to recruit INT to basal bodies of motile cilia which subsequently interacts with actin-modifying proteins such as DAAM1.

1. Delous, M. et al. (2009) Human molecular genetics 18, 4711-23. PMID: 19755384
2. Sang, L. et al. (2011) Cell 145, 513-28. PMID: 21565611
3. Burcklé, C. et al. (2011) Human molecular genetics 20, 2611-27. PMID: 21498478
4. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112
5. Habbig, S. et al. (2011) The Journal of cell biology 193, 633-42. PMID: 21555462
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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