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Anti-XYLT1 Polyclonal Antibody (ARO-A11423)

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概述
货号ARO-A11423
品牌ProteoGenix
描述
Anti-XYLT1 Polyclonal Antibody (ARO-A11423) is a rabbit polyclonal antibody detecting XT-I, XT1, Xylosyltransferase 1, Peptide O-xylosyltransferase 1, XylT-I, XYLT1, Xylosyltransferase I in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human XYLT1 (Gly773-Val910).
靶标XT-I, XT1, Xylosyltransferase 1, Peptide O-xylosyltransferase 1, XylT-I, XYLT1, Xylosyltransferase I
纯化方式Purified by antigen affinity column.
Accession号Q86Y38
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Xylosyltransferase 1 (XYLT1) is a ~107 kDa protein. Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal embryonic and postnatal skeleton development, especially of the long bones. Required for normal maturation of chondrocytes during bone development, and normal onset of ossification.

1. Müller, S. et al. (2005) The Biochemical journal 386, 227-36. PMID: 15461586
2. Pönighaus, C. et al. (2007) The Journal of biological chemistry 282, 5201-6. PMID: 17189265
3. Schreml, J. et al. (2014) Human genetics 133, 29-39. PMID: 23982343
4. Bui, C. et al. (2014) American journal of human genetics 94, 405-14. PMID: 24581741
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-XYLT1 Polyclonal Antibody

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