

| 货号 | ARO-A11427 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CDC23 Polyclonal Antibody (ARO-A11427) is a rabbit polyclonal antibody detecting APC8, Anaphase-promoting complex subunit 8, CDC23, Cell division cycle protein 23 homolog, Cyclosome subunit 8, ANAPC8 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CDC23 (Gly366-Pro597). |
| 靶标 | APC8, Anaphase-promoting complex subunit 8, CDC23, Cell division cycle protein 23 homolog, Cyclosome subunit 8, ANAPC8 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9UJX2 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Cell division cycle protein 23 homolog (CDC23) is a ~68 kDa protein. Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. 1. Jin, L. et al. (2008) Cell 133, 653-65. PMID: 18485873 2. Yau, RG. et al. (2017) Cell 171, 918-933.e20. PMID: 29033132 |
| Note | For research use only. |

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