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Anti-CC2D1A Polyclonal Antibody (ARO-A11479)

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概述
货号ARO-A11479
品牌ProteoGenix
描述
Anti-CC2D1A Polyclonal Antibody (ARO-A11479) is a rabbit polyclonal antibody detecting AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CC2D1A (Pro675-Ser944).
靶标AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A
纯化方式Purified by antigen affinity column.
Accession号Q6P1N0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Coiled-coil and C2 domain-containing protein 1A (CC2D1A) is a ~104 kDa protein. Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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