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Anti-CDC16 Polyclonal Antibody (ARO-A11521)

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概述
货号ARO-A11521
品牌ProteoGenix
描述
Anti-CDC16 Polyclonal Antibody (ARO-A11521) is a rabbit polyclonal antibody detecting CDC16, CDC16 homolog, APC6, Cell division cycle protein 16 homolog, CDC16Hs, ANAPC6, Anaphase-promoting complex subunit 6, Cyclosome subunit 6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CDC16 (Met1-Ser152).
靶标CDC16, CDC16 homolog, APC6, Cell division cycle protein 16 homolog, CDC16Hs, ANAPC6, Anaphase-promoting complex subunit 6, Cyclosome subunit 6
纯化方式Purified by antigen affinity column.
Accession号Q13042
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cell division cycle protein 16 homolog (CDC16) is a ~71 kDa protein. Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.

1. Jin, L. et al. (2008) Cell 133, 653-65. PMID: 18485873
2. Yau, RG. et al. (2017) Cell 171, 918-933.e20. PMID: 29033132
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-CDC16 Polyclonal Antibody

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