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Anti-BAG5 Polyclonal Antibody (ARO-A11536)

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概述
货号ARO-A11536
品牌ProteoGenix
描述
Anti-BAG5 Polyclonal Antibody (ARO-A11536) is a rabbit polyclonal antibody detecting BAG5, KIAA0873, BAG-5, BAG family molecular chaperone regulator 5, Bcl-2-associated athanogene 5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human BAG5 (Met1-Asp248).
靶标BAG5, KIAA0873, BAG-5, BAG family molecular chaperone regulator 5, Bcl-2-associated athanogene 5
纯化方式Purified by antigen affinity column.
Accession号Q9UL15
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

BAG family molecular chaperone regulator 5 (BAG5) is a ~51 kDa protein. Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.

1. Arakawa, A. et al. (2010) Structure (London, England : 1993) 18, 309-19. PMID: 20223214
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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